Molecular classification and therapeutic targets in extrahepatic cholangiocarcinoma

Genome-wide expression analysis of 182 extrahepatic cholangiocarcinoma and 38 non-tumoral bile duct samples as part of a integrated study of gene expression and targeted DNA-sequencing in patients with extrahepatic cholangiocarcinoma We used whole-genome transcriptome to conduct an unsupervised molecular classification of extrahepatic cholangiocarcinoma Formalin-fixed paraffin-embedded samples (primary extrahepatic cholangiocarcinoma and non-tumor bile duct) from patients treated with surgical resection