Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with two F6F molecules in the alpha-site and one F6F molecule in the beta-site

Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with two F6F molecules in the alpha-site and one F6F molecule in the beta-site Descriptor: 1,2-ETHANEDIOL, 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... Authors: Hilario, E, Caulkins, B.G, Young, R.P, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. Deposit date: 2014-11-13 Release date: 2015-11-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water. Biochim.Biophys.Acta, 1864, 2016

鼠伤寒沙门氏菌色氨酸合酶与α位点结合2个F6F分子、β位点结合1个F6F分子的复合物晶体结构。配体信息：1,2-乙二醇、二氢磷酸2-{[4-(三氟甲氧基)苯甲酰基]氨基}乙酯、二(羟乙基)醚等。作者：E·希拉里奥、B·G·考尔金斯、R·P·杨、D·尼克斯、M·F·邓恩、L·J·穆勒、L·范。提交日期：2014-11-13；发布日期：2015-11-18；最后修改日期：2023-09-27。实验方法：X射线衍射（分辨率1.75埃）。引用文献：《利用晶体学技术可视化色氨酸合酶的隧道结构：揭示适配吲哚与排斥水的选择性过滤机制》，《生物化学与生物物理学学报》，2016年，第1864卷。