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KRAS Epitope Identification Immunopeptidomics

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NIAID Data Ecosystem2026-03-12 收录
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Utilizing computational epitope prediction and biochemical assays we predicted and identified high-affinity and/or high-stability KRAS peptides to high prevalence HLA class I molecules. Using single HLA class I allele lines and tumor cell lines in conjunction with MS spectrometry, selected mKRAS epitopes were identified as constituents of the HLA class I ligandome.

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2021-05-29
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