Quantitative analysis of the acinetoabcter baumannii proteome in response to Diclofenac and Colistin

NIAID Data Ecosystem2026-05-02 收录

鲍曼不动杆菌蛋白质组学

耐药性机制

数据链接：

https://www.omicsdi.org/dataset/pride/PXD047586 数据链接链接失效反馈

官方服务：

资源简介：

Quantitative analysis of the acinetoabcter baumannii proteome in response to Diclofenac and Colistin

创建时间：

2024-10-24

低 lncRNA BLACAT1 microRNA-212-5p/EGFR 轴逆转奥希替尼对非小细胞肺癌的耐药性通过 microRNA-212-5p/EGFR 轴逆转非小细胞肺癌

非小细胞肺癌

耐药性机制

一旦出现对奥希替尼的耐药性，非小细胞肺癌（NSCLC）仍然难以治疗。本研究调查了长非编码 RNA BLACAT1如何维持奥希替尼耐药性，并测试靶向BLACAT1是否可以恢复药物敏感性。使用逐步剂量递增产生的PC9-OR和HCC827-OR细胞，我们纵BLACAT1表达并评估活力、迁移/侵袭和信号传导。双荧光素酶测定表明，BLACAT1 充当 microRNA-212-5p 的竞争性内源性 RN

DataCite Commons2025-09-15 更新140

Klebsiella pneumoniae Genome sequencing

细菌基因组测序

耐药性机制

Carbapenem-resistant Klebsiella pneumoniae isolated from Jinling Hospital

NIAID Data Ecosystem70

ibrutinib resistance mantle cell lymphoma [Pt_RNA]. ibrutinib resistance mantle cell lymphoma [Pt_RNA]

套细胞淋巴瘤

耐药性机制

Ibrutinib, a bruton's tyrosine kinase inhibitor, was shown to have high response rates in mantle cell lymphoma (MCL), an aggressive B-cell lymphoma. However, emergence of ibrutinib resistance (IR) and

NIAID Data Ecosystem60

Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia [barcode-seq SG12]

急性髓系白血病

耐药性机制

Targeting the MYST acetyltransferases are an exciting therapeutic opportunity in acute myeloid leukaemia (AML). Here we define the individual and combined contribution of KAT6A, KAT6B and KAT7, in ran

NIAID Data Ecosystem90

Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia

急性髓系白血病

耐药性机制

Allosteric inhibitors of mutant IDH1 or IDH2 induce terminal differentiation of the mutant leukemic blasts and provide durable clinical responses in approximately 40% of acute myeloid leukemia (AML) p

NIAID Data Ecosystem70

Quantitative analysis of the acinetoabcter baumannii proteome in response to Diclofenac and Colistin

资源简介：

相关数据集