RNF8- and Ube2S-dependent ubiquitin lysine 11-linkage modification in response to DNA damage

NIAID Data Ecosystem2026-03-10 收录

DNA损伤修复

泛素化修饰

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Raw images of western blot, immunofluorescence, and live cell images.

创建时间：

2017-05-22

Human Pol Kappa holoenzyme with Ub-PCNA

DNA损伤修复

冷冻电镜结构解析

Human Pol Kappa holoenzyme with Ub-PCNA Descriptor: DNA Primer, DNA Template, DNA polymerase kappa, ... Authors: Lancey, C, De Biasio, A, Hamdan, S.M. Deposit date: 2021-03-15 Release date: 2021-11-03

Protein Data Bank Japan2024-07-10 更新90

DNA damage repair in barley following double-strand breaks and its dependence on ATR

DNA损伤修复

基因组稳定性

Maintaining genome integrity presents a particular challenge for plants due to their sedentary lifestyle, which disables direct avoidance of unfavorable external conditions. Additionally, plants’ meta

NIAID Data Ecosystem50

Data and code for analyzing DSB mobility

DNA损伤修复

肌动蛋白动力学

Double-strand breaks (DSBs) are critical lesions in genomic DNA, and their accurate repair is essential for maintaining genome stability. The nuclear actin cytoskeleton has been implicated in homology

DataCite Commons2025-10-22 更新40

Effect of DNA break-induced transcriptional repression on genome stability. Homo sapiens

DNA损伤修复

染色质调控

Cohesin and the PBAF chromatin remodelling complex are required to repress transcription at sites of DNA double strand breaks. To investigate this and rule out known sister-chromatid dependent functio

NIAID Data Ecosystem60

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

RNF8- and Ube2S-dependent ubiquitin lysine 11-linkage modification in response to DNA damage

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