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A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells though MAPK activation.

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下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJEB3024
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资源简介:
A MET amplified gastric cancer cell line, GTL16, was made resistant to c-Met inhibition with prolonged exposure to a c-Met inhibitor, PF- 04217903 (METi). Sequencing of surviving cells identified a fusion transcript between SND1 and BRAF.
创建时间:
2012-06-23
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