Cost of HLA-B*15∶02 screening compared with mammography and Pap smear.

1Upper-limit cost of HLA-B*15∶02 screening to prevent one death was estimated from overall SJS/TEN mortality rate at 5%, and 30% mortality rate was used for lower-limit. 2Costs were converted from UK sterling to US dollars using the May 2004 exchange rate of £0.56 to $1. †Excluded costs of diagnostic screening, biopsy and all subsequent procedures if any abnormality was found. #Cost for an additional consultation was included based on the observed 98.6% non-same-day test turnaround rate. SJS, Stevens-Johnson Syndrome; TEN, toxic epidermal necrolysis.