Long-read sequencing of Plasmodium falciparum clones
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP404519
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资源简介:
Sequence variation among antigenic var genes in Plasmodium falciparum drives ineffective host immune responses to malaria. Using long reads, we detect unexpected var polymorphism within 17 parasite clones from a mutation accumulation experiment. Putatively circular DNA from these clones is strongly enriched for var genes, which appear in numerous alleles separated by recombination and indel events.
创建时间:
2023-08-13



