Mus musculus Raw sequence reads. Mus musculus

NIAID Data Ecosystem2026-03-12 收录

抗肿瘤免疫

CDK2抑制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA738675 数据链接链接失效反馈

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资源简介：

CDK2 inhibition enhances anti-tumor immunity by increasing interferon response to endogenous retroviruses

创建时间：

2021-06-17

Sc-RNA seq of mouse splenic NK cells

NK细胞转录组

抗肿瘤免疫

In this study, we demonstrate that depletion of grp94 in NK cells lead to immaturities and weakened anti-tumor function of NK cells. To talidate our assumption, sc-RNA-seq was performed on NK cells FA

NIAID Data Ecosystem80

Interleukin-12 bypasses common gamma-chain signaling in emergency natural killer cell lymphopoiesis. Effects of IL-12 on NK cells

NK细胞发育

抗肿瘤免疫

Differentiation and homeostasis of natural killer (NK) cells relies on common gamma-chain (γc)-dependent cytokines, in particular IL-15. Consequently, NK cells do not develop in mice with targeted γc

NIAID Data Ecosystem40

Metastasis Ingesting Macrophages

抗肿瘤免疫

细胞吞噬作用

Comparison of Macrophages from lungs 24hrs post-injection with B16-F10 Melanoma Cells expressing the Fluoresence Protein ZsGreen. ZsGreen+ and ZsGreen- macrophages were sorted and transcriptome compar

NIAID Data Ecosystem00

Modification of anti-tumor immunity by tolerogenic dendritic cells

免疫调节

抗肿瘤免疫

Immunosuppressive functions of glucocorticoids (GC) can be mediated via various mechanisms, including the modulation of dendritic cells (DC). Our study investigates the effects of tolerogenic GC-treat

DataCite Commons2020-09-02 更新80

Systemically primed central memory T cells source intranasally boosted tissue-resident memory T cells against melanoma lung metastasis

抗肿瘤免疫

记忆T细胞分化

Tissue resident memory T (TRM) cells mediate the frontline protection against melanoma lung metastasis. We utilized scRNA-seq to investigate the underlying molecular mechanism of central memory T (TCM

NIAID Data Ecosystem10

Mus musculus Raw sequence reads. Mus musculus

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