RNAseq analysis of transcriptome changes in MM27 metastatic melanoma PDX cells upon treatment with AURKA and/or MEK inhibitors
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https://www.ncbi.nlm.nih.gov/sra/SRP385277
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Purpose: Study the changes in the transcriptome of metastatic melanoma PDX cells upon combination treatment with AURKA and MEK inhibitors Methods: RNAseq analysis of melanoma PDX cells treated with AURKA inhibitor Alisertib (500nM) and MEK inhibitor trametinib (100nM) for 72 h Overall design: Actionable genetic screens unveil the dual targeting of AURKA and MEK as an alternative therapeutic approach for melanoma treatment
创建时间：
2023-07-07
