CS Home Training data.xlsx

After baseline measurements in-lab, participants were sent home to train for several months (subacute (SA): 4.9±0.6 months [mean ± SD]; chronic (CH): 6.8±4.0 months). They used their personal computers with a chin/forehead-rest provided by the lab, which they were instructed to position 42cm away from their display during training. Participants performed 300 trials of their assigned training tasks (Static, Motion or Flicker) per location per day, at least five days per week, and they emailed their data log files back to the lab for analysis every week. During home training sessions, they were instructed to stay fixated on the fixation spot and warned that inadequate fixation accuracy could limit recovery.Session thresholds were calculated by fitting a Weibull function with a 72.5 percent correct performance threshold criterion. After participants’ thresholds improved consistently for at least 20 sessions, we moved their training stimulus 1˚ deeper into the blind field along the x-axis (Cartesian coordinate space). Because the diameter of the stimulus is 2.5 ˚, the new training location had ~80% overlap with the original training location. Once participants trained for about 4 months, with at least one improved location (defined as consistently good contrast thresholds at that location), they were brought back to the lab, and performance at all home-trained locations was verified with eye tracker-enforced fixation control. We aimed for a similar number of training sessions at the blind-field locations of interest before scheduling people to return for in-lab performance verification. However, the amount of time elapsed until the return visit did vary, as it was affected by the individual’s rate of improvement, their work/family schedules, and ability to travel to our single study site (participants originated from across the entire United States and Canada). All participants were best corrected using glasses or contact lenses during testing and training. The Research Subjects Review Board approved study procedures at the University of Rochester, which were conducted as per the Declaration of Helsinki, with written informed consent obtained from each participant, and participation was voluntary.在实验室完成基线测量后，受试者被带回家进行数月训练（亚急性（subacute, SA）组：4.9±0.6个月[均值±标准差]；慢性（chronic, CH）组：6.8±4.0个月）。受试者使用实验室提供的带有下颌/前额支撑的个人电脑，训练期间需将设备摆放至距离显示屏42厘米的位置。每日针对每个训练位置完成指定训练任务（静态、运动或闪烁任务）的300次试次，每周至少训练5天，并每周通过电子邮件将数据日志文件发送至实验室以供分析。在家训练过程中，受试者需始终固视注视点，同时被告知固视精度不足可能会影响康复效果。我们通过拟合正确率阈值为72.5%的威布尔（Weibull）函数来计算会话阈值。当受试者的阈值在至少连续20个训练会话中持续改善后，我们将训练刺激沿笛卡尔坐标空间的x轴向视野盲区深处移动1°。由于刺激直径为2.5°，新的训练位置与原训练位置存在约80%的重叠。待受试者训练约4个月，且至少存在一个性能得到改善的训练位置（定义为该位置的对比度阈值持续处于良好水平）时，我们将其召回实验室，通过眼动仪强制固视控制，验证所有在家训练位置的表现。在安排受试者返回实验室进行性能验证前，我们力求在感兴趣的视野盲区位置设置相近数量的训练会话。不过，受试者返回实验室的间隔时长存在差异，这受到个体康复速度、工作/家庭日程安排以及前往我们唯一研究站点的出行能力影响（受试者来自美国和加拿大全境）。所有受试者在测试与训练期间均佩戴眼镜或隐形眼镜以达到最佳矫正视力。本研究流程经罗切斯特大学研究受试者审查委员会批准，严格遵循《赫尔辛基宣言》开展，所有受试者均已签署书面知情同意书，且参与研究完全自愿。