A summary of the pharmacological response to emodepside in transgenic lines expressing either <i>C. elegans</i> or parasite <i>slo-1</i> under the control of <i>C. elegans</i>-derived promoters.

The data given are the Hill slope, EC50 and bottom values for the four parameter logistic inhibition curves with 95% confidence intervals. Top values were always close to 100% due to normalization to the highest absolute value in each data set. The values were determined from pooled data for 3 experiments. #For both A. caninum experiments, the same N2 control was used. *Since all curves were significantly different from slo-1(js379) (p<0.0001), which did not show a concentration-dependent response at all, this comparison is not listed here. xComparisons were done for all four parameters of a concentration-response-curves (Hill slope, EC50, top and bottom). If significant differences were obtained with this calculation, separate comparisons for EC50 and bottom followed.