sestrin2 drives ER-phagy in response to protein misfolding

NIAID Data Ecosystem2026-05-02 收录

内质网自噬

蛋白质错误折叠

数据链接：

https://data.mendeley.com/datasets/gg7cnt2fyd 数据链接链接失效反馈

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资源简介：

Uncropped western blots data for Sestrin2 drives ER-phagy in response to protein misfolding

创建时间：

2024-06-19

Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice

神经退行性机制

蛋白质错误折叠

Age-related neurodegenerative diseases (NDDs) and neuronal dysfunction are associated with the aggregation and propagation of specific pathogenic protein species (e.g. AÃ, a-synuclein, tau). However,

NIAID Data Ecosystem130

FAM134B oligomerization drives endoplasmic reticulum membrane scission for ER-phagy

内质网自噬

膜断裂机制

Degradation of Endoplasmic Reticulum (ER) by selective autophagy (ER-phagy) is crucial for ER homeostasis. However, it remains unclear how ER scission is regulated for subsequent autophagosomal seques

NIAID Data Ecosystem60

Identification and Glycerol-Induced Correction of Misfolding Mutations in the X-Linked Mental Retardation Gene CASK

蛋白质错误折叠

智力障碍基因突变分析

The overwhelming amount of available genomic sequence variation information demands a streamlined approach to examine known pathogenic mutations of any given protein. Here we seek to outline a strateg

Figshare2016-01-18 更新40

amd_B1_ff14SB_TIP3P_MISFOLDED.in

分子动力学模拟

蛋白质错误折叠

input file for amd simulation of B1 with ff14SB_TIP3P starting from misfolded

DataCite Commons2024-06-22 更新80

Enzymatic Blockade of the Ubiquitin-Proteasome Pathway

泛素-蛋白酶体通路

蛋白质错误折叠

Ubiquitin-dependent processes control much of cellular physiology. We show that expression of a highly active, Epstein-Barr virus-derived deubiquitylating enzyme (EBV-DUB) blocks proteasomal degradati

Figshare2016-01-18 更新50

sestrin2 drives ER-phagy in response to protein misfolding

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