Crystal structure of Dengue virus serotype 3 RNA dependent RNA polymerase bound to HeE1-2Tyr, a new pyridobenzothizole inhibitor
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Crystal structure of Dengue virus serotype 3 RNA dependent RNA polymerase bound to HeE1-2Tyr, a new pyridobenzothizole inhibitor Descriptor: N-[8-(cyclohexyloxy)-1-oxo-2-phenyl-1H-pyrido[2,1-b][1,3]benzothiazole-4-carbonyl]-L-tyrosine, RNA dependent RNA polymerase, ZINC ION Authors: Tarantino, D, Mastrangelo, E, Milani, M. Deposit date: 2016-03-10 Release date: 2016-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor. Antiviral Res., 134, 2016
登革病毒3型RNA依赖的RNA聚合酶(RNA dependent RNA polymerase)结合新型吡啶并苯并噻唑类抑制剂HeE1-2Tyr的晶体结构
描述符:N-[8-(环己氧基)-1-氧代-2-苯基-1H-吡啶并[2,1-b][1,3]苯并噻唑-4-羰基]-L-酪氨酸、RNA依赖的RNA聚合酶、锌离子(ZINC ION)
作者:Tarantino, D、Mastrangelo, E、Milani, M.
存入日期:2016-03-10
发布日期:2016-10-05
末次修改日期:2024-05-08
实验方法:X射线衍射(分辨率3 Å)
引用文献:《通过吡啶并苯并噻唑类抑制剂靶向黄病毒RNA依赖的RNA聚合酶》,《抗病毒研究》,第134卷,2016年
创建时间:
2016-03-10



