Draft genome assembly dataset of four prospective probiotic Bifidobacterium strains

Draft genome sequences dataset of four Bifidobacterium strains is presented. Genomic DNA was isolated from pure cultures of four Bifidobacterium strains from Russian National Collection of Industrial Microorganisms (VKPM): B. adolescentis VKPM=Ac-1245, B. bifidum VKPM=Ac-1579, B. longum subsp. longum VKPM=Ac-1635, B. bifidum VKPM=Ac-1784. Genome sequencing was performed on Illumina Miseq system. De novo genome assembly and annotation was made using ZGA pipeline (https://github.com/laxeye/zga/) and resulted in four high-quality draft genomes with high completeness and low contamination levels. Genes related to utilization of human milk oligosaccharides and mucin were identified as well as bite salt hydrolase. Genome of B. bifidum VKPM=Ac-1784 showed presence of two putative bacteriocin gene clusters.本数据集公开了四株双歧杆菌（Bifidobacterium）的草图基因组序列。研究人员从俄罗斯国家工业微生物保藏中心（Russian National Collection of Industrial Microorganisms, VKPM）保藏的四株双歧杆菌纯培养物中提取了基因组DNA，对应菌株分别为青春双歧杆菌（B. adolescentis）VKPM=Ac-1245、两歧双歧杆菌（B. bifidum）VKPM=Ac-1579、长双歧杆菌长亚种（B. longum subsp. longum）VKPM=Ac-1635以及两歧双歧杆菌（B. bifidum）VKPM=Ac-1784。基因组测序在Illumina Miseq平台上完成，采用ZGA分析流程（https://github.com/laxeye/zga/）完成了从头基因组组装与注释，最终获得4株高质量草图基因组，其基因组完整性高且污染率低。本研究同时鉴定出了与人类母乳低聚糖、黏蛋白利用相关的基因以及胆汁盐水解酶基因。两歧双歧杆菌VKPM=Ac-1784的基因组中存在两个潜在的细菌素基因簇。