Efficacy of hydrocolloid dressing for prophylactic use of hand-foot skin reaction induced by multi targeted kinase inhibitors: a phase III self-controlled study

Interventions: In addition to the standard care of moisturizing, attach a hydrocolloid dressing for 1 month from the start of multi-kinase inhibitor therapy. the standard care of moisturizing Primary outcome(s): Proportion of grade 2 or higher hand-foot syndrome (only sole) Study Design: Parallel Randomized