P-type ATPases function to provide homeostasis in higher eukaryotes, but they are essentially ubiquitous, being found in all domains of life. Thever and Saier [J Memb Biol 2009;229:115–130] recently r
‘N’ and ‘C’ denote the N- and C-terminal element respectively. ‘Core-1TM’ denotes proteins with exactly one TM after the core (only class IA). ‘Broken core’ counts sequences with less than 6 TM in the
The basolateral membranes of Aplysia californica foregut absorptive cells contain both Cl(-)-stimulated ATPase and ATP-dependent Cl- transport activities, and each was inhibited by orthovanadate. Both