aNSG mice injected i.p. with control empty liposomes or liposomes loaded with IL-12. The dose of IL-12 was 50 µg/mouse. All mice were treated 21 days after i.p. injection of the tumor-derived cell agg
Resistance to the currently available treatment paradigms is one of the main factors that contributes to poor outcomes in patients with advanced cervical cancer. Novel targeted therapy approaches migh
Anti-TNF therapies are a core anti-inflammatory approach for chronic diseases such as rheumatoid arthritis and Crohn’s Disease. Previously, we and others found that TNF blocks the emergence and functi
Immune checkpoint inhibitors (ICIs) represented by anti-PD-1/PD-L1 antibodies have been widely applied for various cancers and the response rate to ICIs is closely associated with the tumor immune mic
