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Single molecule analysis reveals functionally relevant isoforms of telomerase RNA in moss

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NIAID Data Ecosystem2026-05-01 收录
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The goal of the study is to determine the secondary structure of telomerase RNA in P. patens in vivo (using DMS-Seq) or in vitro (using SHAPE-Seq). cDNA with induced mutations was generated with TGIRT-II or Superscript-II in the presence of MnCl2 (SHAPE-Seq). Samples for sequencing were prepared in biological triplicates.

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2023-10-02
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