Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

Protein Data Bank Japan2024-02-28 更新2026-03-21 收录

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Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop Descriptor: Acriflavine resistance protein B, DARPIN, DECANE, ... Authors: Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M. Deposit date: 2012-02-27 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.253 Å) Cite: Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc.Natl.Acad.Sci.USA, 109, 2012

多药转运蛋白AcrB（multidrug transporter AcrB）介导的药物转运过程包含一个接入口袋与一个深结合口袋，二者由转换环（switch-loop）分隔。描述符：吖啶橙抗性蛋白B（Acriflavine resistance protein B）、DARPIN、癸烷（DECANE）等作者：Eicher T、Cha H、Seeger M.A、Brandstaetter L、El-Delik J、Bohnert J.A、Kern W.V、Verrey F、Gruetter M.G、Diederichs K、Pos K.M 提交日期：2012-02-27 发布日期：2012-05-02 最后修改日期：2024-02-28 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.253埃（Å）引用文献：多药转运蛋白AcrB介导的药物转运过程包含一个接入口袋与一个深结合口袋，二者由转换环分隔。《美国国家科学院院刊》（Proc.Natl.Acad.Sci.USA），第109卷，2012年

创建时间：

2012-02-27