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RNAi knock down of the DNA-repair enzyme and transcriptional co-activator APE1 in human HeLa cells

ChEBI2009-02-02 更新2026-07-21 收录

DNA损伤修复机制

RNA干扰机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MEXP-1315 数据链接链接失效反馈

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资源简介：

RNAi knock down of the DNA-repair enzyme and transcriptional co-activator APE1 in human HeLa cells

应用场景：

创建时间：

2009-02-02

蛋白质-RNA复合物结构

RNA干扰机制

Argonaute proteins lie at the heart of the RNA-Induced Silencing Complex (RISC), wherein they use small RNA guides to recognize targets. Some Argonaute proteins can directly cleave their targets, wher

NIAID Data Ecosystem100

Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice. Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice

DNA损伤修复机制

单核苷酸分辨率基因组学

In the present work we have applied analytical methods to map repair events in rDNA using data generated by the newly developed XR-seq genome-wide single nucleotide repair technology. We find that in

NIAID Data Ecosystem60

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

酶-RNA复合物结构

DNA损伤修复机制

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

NIAID Data Ecosystem50

FAN1 R507H-PCNA-DNA_minimum-dataset

DNA损伤修复机制

冷冻电镜结构解析

This minimum cryo-EM dataset is used in the research of 'Structural and molecular basis of PCNA-activated FAN1 nuclease function in DNA repair'.

Figshare2025-02-10 更新70

DEPS-1 promotes P granule assembly and RNA interference in C. elegans germ cells

昆虫生殖细胞发育

RNA干扰机制

P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss

Alliance of Genome Resources50

RNAi knock down of the DNA-repair enzyme and transcriptional co-activator APE1 in human HeLa cells

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