five

Training phages to overcome the growth-infectivity trade-off

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP300125
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To address the possibility for single phage isolates to evolve both high growth rate and broadly infectivity, we worked with the lytic phage Pseudomonas phage phi-2, which infects the bacterium Pseudomonas fluorescens SBW25. Three types of training strategies were adopted here: evolution on susceptible bacteria, coevolution with bacteria, and rotation between evolution- and coevolution-phases.
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2021-01-15
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