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Inflammatory Response in White Adipose Tissue in the Non-Obese Hormone-Sensitive Lipase Null Mouse Model

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https://figshare.com/articles/dataset/Inflammatory_Response_in_White_Adipose_Tissue_in_the_Non_Obese_Hormone_Sensitive_Lipase_Null_Mouse_Model/3072202
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资源简介:
In the present study, a local inflammatory response in white adipose tissue from the nonobese HSL-null mouse model is demonstrated. The protein levels of several well-known markers of inflammation, like TNFα and ferritin HC, were highly increased and accompanied by an activation of NFκB. A number of macrophage proteins, i.e., gal-3, Capg, and MCP-4, were expressed at increased levels and immunohistochemical analyses revealed an increased infiltration of F4/80+ cells.Keywords: hormone-sensitive lipase • white adipose tissue • proteomics • retinoic acid • inflammation
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2016-03-01
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