PFN4 is required for acrosome biogenesis by regulating autophagy through PI3K/AKT/mTOR pathway
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.omicsdi.org/dataset/pride/PXD030394
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资源简介:
We generated Pfn4 knockout mice and showed that male mice are infertile and acrosome biogenesis is impaired from first phase of Development (Golgi-phase). Autophagy participates in acrosome formation and LC-MS data showed proteins related to autophagy, PI3K/AKT signaling and mTOR are enriched in PFN4-/- male mice.
创建时间:
2022-08-15



