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Pool-seq of Experimentally Evolved P. aeruginosa PA14 Populations in LB

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https://www.ncbi.nlm.nih.gov/sra/SRP349428
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Experimental evolution was used to understand, and test the genetic requirements, of the rapid rise of LasR- lineages of P. aeruginosa in LB medium. Evolutions were seeded with either WT PA14, a cbrA mutant or a cbrB mutant, and on the 2nd and 3rd passages (on Days 4 and 6 of the evolutions, respectively) whole genomes were sequenced from the evolved pools to identify mutations that increased in proportion over the course of the evolution.
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2022-05-06
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