Mean cumulative number of cases in the metropolitan U.S. under travel restriction and vaccination intervention scenarios.

Base R0 = 1.7.
1N: no intervention, TO: 95% travel restriction only, VO: 0.1% vaccination only, TV: both 95% travel restriction and 0.1% vaccination
2The end of the epidemic is determined when there are no further cases worldwide.
3These data represent means and standard deviations for all 100 runs, including the runs in which the disease did not develop a pandemic state and did not reach the U.S.