Steap3
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1551194
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资源简介：
Enables cupric reductase (NADH) activity and ferric-chelate reductase (NADPH) activity. Acts upstream of or within exosomal secretion; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and transition metal ion transport. Located in endosome membrane and plasma membrane. Is expressed in several structures, including bone; genitourinary system; liver; nervous system; and white fat. Orthologous to human STEAP3 (STEAP3 metalloreductase). [provided by Alliance of Genome Resources, Nov 2024]
激活铜还原酶（NADH）活性和铁螯合还原酶（NADPH）活性。作用于外泌体分泌的上游或其中；在DNA损伤响应中，由p53类介质正向调控内源性的细胞凋亡信号通路；以及过渡金属离子转运。定位于内体膜和质膜。在多个结构中表达，包括骨骼；泌尿生殖系统；肝脏；神经系统；以及白色脂肪。与人源STEAP3（STEAP3金属还原酶）同源。[由基因组资源联盟提供，2024年11月]
提供机构：
Rat Genome Database
