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PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

NIAID Data Ecosystem2026-05-02 收录

胰腺导管腺癌

PLK1/MAPK通路抑制

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Original Western Blot Images from the figures displayed in the manuscript: PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

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2025-02-27

肿瘤免疫治疗

胰腺导管腺癌

A multi-omic analysis of CITE-seq of a syngeneic model of PDAC unveils distinct phenotypic correlations of augmented anti-tumor immunity and a substantially reduced immunosuppressive tumor microenviro

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Supplementary Figure S1: Bioanalyzer Results obtained from PDAC compartments.(A) Human brain total RNA Was obtained from ThermoFisher nd diluted to 625pg/μl (left) and 312. 5pg/μl (right), Which was the expected range for total RNA Recovery from PDAC Compartments. Small RNA And ribosomal RNA Peaks are indicated. Total RNA Recovery from tumor (B), Stroma (C), And microvasculature (D). Recovery Was highest from 271, 100Μm 2 Tumor compartment compared to stroma and microvasculature.Supplementary data

RNA分析

胰腺导管腺癌

NIAID Data Ecosystem40

Bulk RNA sequencing of GFER / ALR deletion in human pancreatic ductal adenocarcinoma cells

胰腺导管腺癌

基因转录调控

The goal is to assess the transcriptional impact of GFER / ALR deletion to human pancreatic ductal adenocarcinoma cells.

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Repeat RNA infection

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分子信号传导

Aberrant expression of repeat RNAs in pancreatic ductal adenocarcinoma (PDAC) mimic viral-like responses with implications on tumor cell state and the response of the surrounding microenvironment. To

DataCite Commons2025-05-01 更新40

ena-DATASET-SLC-22-06-2017-12:04:40:959-248 - samples

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胰腺导管腺癌

RNAseq dataset of 34 samples (6 normals, 7 stroma-enriched, 21 malignant cells-enriched) from patients with resected pancreatic ductal carcinoma.EGA dataset EGAD00001003399

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PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

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