Cyclin A binding groove inhibitor H-Arg-Arg-Leu-Ile-Phe-NH2
收藏NIAID Data Ecosystem2026-05-02 收录
数据链接:
官方服务:
资源简介:
Cyclin A binding groove inhibitor H-Arg-Arg-Leu-Ile-Phe-NH2
应用场景:
创建时间:
2024-11-13
相关数据集
Formation of a structurally-stable conformation by the intrinsically disordered MYC:TRRAP complex
Our primary goal is to therapeutically target the oncogenic transcription factor MYC to stop tumor growth and cancer progression. Here, we report aspects of the biophysical states of the MYC protein a
NIAID Data Ecosystem70
Discovery of Selective Small-Molecule Inhibitors for the β‑Catenin/T-Cell Factor Protein–Protein Interaction through the Optimization of the Acyl Hydrazone Moiety
Acyl hydrazone is an important functional group for the discovery of bioactive small molecules. This functional group is also recognized as a pan assay interference structure. In this study, a new sma
Figshare2016-02-13 更新30
Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions
Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions Descriptor: 5-[3-chloro-4-({4-[1-(3,4-dichlorophenyl)-1H-pyrazol-5-yl]benzyl}carbamothioyl)phenyl]f
Protein Data Bank Japan2023-09-20 更新20
Menin in complex with MI-389
Menin in complex with MI-389 Descriptor: 2-{2-cyano-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indol-1-yl}aceta mide, DI(HYDROXYETHYL)ETHER, DIMETHYL S
Protein Data Bank Japan2023-09-27 更新40
Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein–Protein Interactions with Heat Shock Protein 70 (Hsp70)
Cancer cells rely on the chaperone heat shock protein 70 (Hsp70) for survival and proliferation. Recently, benzothiazole rhodacyanines have been shown to bind an allosteric site on Hsp70, interrupting
Figshare2018-07-13 更新20



