This dataset contains experimental pain threshold measurements and classical pain model data collected from 125 healthy adult volunteers under both baseline and chemically-sensitized conditions. The d
Sensitization of primary afferent neurons underlies much of the pain and tenderness associated with tissue injury and inflammation. The increase in excitability is caused by chemical agents released a
Numerous studies have demonstrated a positive correlation between sleep disorders and hyperalgesia. These sleep disorders adversely affect the descending pain regulatory system. Researchers have exten
