Neonatal morbidity among preterm prelabor rupture of membrane pregnancies according to the presence or absence of microbial-associated intraamniotic inflammation, sterile intraamniotic inflammation and microbial invasion of the amniotic cavity alone.

Abbreviations: IAI: Intraamniotic inflammation, MIAC: microbial invasion of the amniotic cavity. Severe neonatal morbidity was defined as a need for intubation and/or respiratory distress syndrome and/or pneumonia and/or bronchopulmonary dysplasia and/or intraventricular hemorrhage and/or necrotizing enterocolitis and/or early-onset sepsis and/or late-onset sepsis and/or neonatal death before hospital discharge. Retinopathy of prematurity (n = 1) and late onset sepsis (n = 2) was not considered in the analysis because of low occurrence in the cohort. Categorical variables were compared using the Fisher’s exact test or the chi-square test. Spearman partial correlation was used to adjust the data for the gestational age at delivery. Statistically significant results are marked in bold. p-value1: the comparison among four groups with the Fisher’s exact tests (exact 2-tailed p-value). p-value2: the comparison among four groups with the adjustment for gestational age at delivery. p-value3: the comparison among women with microbial-associated intraamniotic inflammation, microbial invasion of the amniotic cavity alone, and negative women with the chi-square test. p-value4: the comparison among women with microbial-associated intraamniotic inflammation, microbial invasion of the amniotic cavity alone, and negative women with the adjustment for gestational age at delivery.
Neonatal morbidity among preterm prelabor rupture of membrane pregnancies according to the presence or absence of microbial-associated intraamniotic inflammation, sterile intraamniotic inflammation and microbial invasion of the amniotic cavity alone.