WNV H8912 exhibited a significantly reduced neurovirulence.
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A. Mice were injected i.c. with different doses of WNV H8912 and monitored twice daily. B–C. Mouse primary cortical neuron/glia cultures were infected with WNV H8912 and its wild-type controls WNV NY99. Viral load at indicated time points post-infection was determined by Q-PCR assay (B) or by plaque assay (C). Data are presented as means ± SEM, n = 3. * P<0.05 or **P<0.01 compared to WNV NY99-infected cells.
创建时间：
2013-06-13
