GSE19697 Expression Data

An expression profile that predicts the therapeutic response of the basal-like breast cancer to neoadjuvant chemotherapy. Core biopsies were obtained from 86 patients prior to neoadjuvant therapy out of which 70 fulfilled the requirements to undergo expression analysis (24 of these 70 were used in the published analysis). pCR was defined as no residual invasive disease in the breast or lymph nodes. Residual in situ carcinoma was also considered as pCR. RNA was extracted from snap frozen 14-gauge core samples obtained from pre-treatment tumors. Specimens containing more than 40% of tumor on histological examination were analyzed.