Wild-type and IVA-PLA2-knockout (KO) mice were fed normal (N) or high-fat (HF) diets for 16 weeks and fasted. The serum levels of PGE2 were measured (n = 3–5). aP<0.05 versus wild-type mice fed normal
Peeling Skin Disease (PSD; OMIM 270300) is an inflammatory ichthyosis due to homozygous loss-of-function mutations in Corneodesmosin (CDSN) and characterized by lifelong patchy peeling of the skin ass
