Impact of GNA13 overexpression on gene expression changes in LNCaP cells

GNA13 has been shown to have multiple oncogenic roles in many different solid tumors including prostate cancers. However, the molecular mechanisms that drive GNA13-induced oncogenesis and metastasis is not understood completely. To elucidate the mechanisms driven by GNA13 in prostate cancer cells, we performed total RNA sequencing in LNCaP cells after overexpressing the wild-type GNA13 cDNA in a pBabe-puromycin vector. RNA sequencing of LNCaP cells stably expressing pBabe-GNA13 or pBabe-vector, each in three biological replicates