Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0036805-001 (A71EV2A-x4735)

Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0036805-001 (A71EV2A-x4735) Descriptor: 1-[(2R)-2-(1H-imidazol-5-yl)pyrrolidin-1-yl]-2-[2-(methylsulfanyl)phenyl]ethan-1-one, DIMETHYL SULFOXIDE, Protease 2A, ... Authors: Lithgo, R.M, Fairhead, M, Koekemoer, L, Balcomb, B.H, Capkin, E, Chandran, A.V, Golding, M, Godoy, A.S, Aschenbrenner, J.C, Marples, P.G, Ni, X, Thompson, W, Tomlinson, C.W.E, Wild, C, Winokan, M, Xavier, M.-A.E, Kenton, N, Tucker, J, DiPoto, M, Lee, A, Fearon, D, von Delft, F. Deposit date: 2025-03-12 Release date: 2025-04-02 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (1.219 Å) Cite: Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre To Be Published本数据集为柯萨奇病毒A16（Coxsackievirus A16）G-10株2A蛋白酶（protease 2A）与ASAP AViDD中心来源抑制剂的共沉积晶体结构——柯萨奇病毒A16（G-10株）2A蛋白酶与ASAP-0036805-001（A71EV2A-x4735）复合物的晶体结构。组分描述：1-[(2R)-2-(1H-咪唑-5-基)吡咯烷-1-基]-2-[2-(甲硫基)苯基]乙-1-酮、二甲基亚砜（dimethyl sulfoxide）、2A蛋白酶等。作者：Lithgo R.M、Fairhead M、Koekemoer L、Balcomb B.H、Capkin E、Chandran A.V、Golding M、Godoy A.S、Aschenbrenner J.C、Marples P.G、Ni X、Thompson W、Tomlinson C.W.E、Wild C、Winokan M、Xavier M.-A.E、Kenton N、Tucker J、DiPoto M、Lee A、Fearon D、von Delft F。沉积日期：2025-03-12；发布日期：2025-04-02；最后修改日期：2025-04-09。实验方法：X射线衍射（1.219 Å）。引用说明：柯萨奇病毒A16（G-10株）2A蛋白酶与ASAP AViDD中心来源抑制剂的共沉积 待发表。