RNA-seq of Serine metabolism reprogramming in colorectal cancer
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA682868
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资源简介:
We performed transcriptome profiling by RNA sequencing (RNA-seq) in SW620-S and SW620 cells, to gain insight into the molecular basis of serine deprivation resistance. To examine the hypothesis that increased PHGDH meets the requirement of cells cultured in serine-depleted media for multiplication, we treated cells with CBR5884 and performed transcriptome profiling. YAP was activated in SW620-S cells. To study the role of YAP in serine deprivation resistant cells , we treated cells with Verteporfin(VP) to explore the changes of genes.
创建时间:
2020-12-06



