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Retinoic acid signaling is essential for HSC development

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To find signaling regulators that modulate transition from endothelial (AA4.1/VEC+CD45-) to hemogenic endothelial (AA4.1/VEC+ CD45+) cell This microarray was performed between AA4.1/VEC single +ve or AA4.1/VECCD45+ cells were sorted from E11.5 AGM and Total RNA was extracted.

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