RNA-seq in neutrophils from patients with intracranial aneurysms

In this study, we explored transcriptional differences in human neutrophils from patients with intracranial aneurysms and a demographic and comorbidity paired population of controls We compared differentially expressed genes among neutrophils from 11 blood samples from patients with intracranial aneurysms and 11 blood samples from paired controls. We used an independent, unpaired, corroboration cohort of 5 intracranial aneurysm patients and 5 control patients to confirm our findings.