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Expression Profiles of HepG2 cells treated with 7 compounds

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE163130
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The transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo published by Magkoufopoulou et al (2012) was validated by the independent study performed in HepG2 cells for which the gene expression data are described here. The data were reanalyzed for the OpenRiskNet project (Horizon2020 EINFRA-22-2016 Programme; Grant Agreement 731075). The study investigated differential gene expression in HepG2 cell line mRNA following 24 and 48 hours of exposure to 2 genotoxic carcinogens, 2 non-genotoxic carcinogens, 3 non-genotoxic non-carcinogens and their solvents. Three biological replicates per compound/solvent. In total 54 arrays.
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2020-12-19
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