Brain Region-Specific Gene expression in Exercise for a Mouse Model of Parkinson's Disease
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https://www.ncbi.nlm.nih.gov/sra/SRP379730
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Exercise plays an essential role in improving motor symptoms in Parkinson's disease (PD), but the mechanism in the central nervous system remains obscure. We tested effects of 12-week treadmill exercise on a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of PD and observed a significant improvement in motor ability. Here we performed RNA-sequencing on 4 brain regions from control animals, MPTP-induced PD mice and MPTP-induced PD mice treated with exercise for 12 weeks. Overall design: RNA-sequencing on 4 brain regions from control animals, MPTP-induced PD mice and MPTP-induced PD mice treated with exercise for 12 weeks were performed
创建时间：
2022-07-14
