X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine

Protein Data Bank Japan2023-12-20 更新2026-03-21 收录

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X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine Descriptor: Bromomemantine, Cys-loop ligand-gated ion channel Authors: Ulens, C, Spurny, R, Thompson, A.J, Alqazzaz, M, Debaveye, S, Lu, H, Price, K, Villalgordo, J.M, Tresadern, G, Lynch, J.W, Lummis, S.C.R. Deposit date: 2014-06-30 Release date: 2014-09-24 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.901 Å) Cite: The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine. Structure, 22, 2014

菊欧文氏菌（Erwinia chrysanthemi）来源的五聚体配体门控离子通道（pentameric ligand-gated ion channel，缩写ELIC）与溴美金刚（bromomemantine）形成复合物的X射线晶体结构描述：溴美金刚、半胱氨酸环（Cys-loop）配体门控离子通道作者：Ulens, C、Spurny, R、Thompson, A.J、Alqazzaz, M、Debaveye, S、Lu, H、Price, K、Villalgordo, J.M、Tresadern, G、Lynch, J.W、Lummis, S.C.R. 提交日期：2014-06-30 发布日期：2014-09-24 最后修改日期：2023-12-20 实验方法：X射线衍射（分辨率3.901埃）引用文献：《阿尔茨海默病药物美金刚捕获处于孔道阻断剂结合构象的原核生物配体门控离子通道ELIC》，*Structure*，22卷，2014年

创建时间：

2014-06-30