Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units. Respiratory Metagenomics using nanopore sequencing

Clinical metagenomics using nanopore sequencing was evaluated in a proof-of-concept study on 43 respiratory samples from 34 intubated patients across seven intensive care units over a 9 week period during the first COVID-19 pandemic wave.