Crystal structure of protein tyrosine phosphatase 1B with potent and selective bidentate inhibitor compound 2

Protein Data Bank Japan2023-08-16 更新2026-03-21 收录

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Crystal structure of protein tyrosine phosphatase 1B with potent and selective bidentate inhibitor compound 2 Descriptor: ACETIC ACID, MAGNESIUM ION, N-{1-[5-(1-CARBAMOYL-2-MERCAPTO-ETHYLCARBAMOYL)-PENTYLCARBAMOYL]-2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ETHYL}-3-{2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ACETYLAMINO}-SUCCINAMIC ACID, ... Authors: Sun, J.P, Fedorov, A, Lee, S.Y, Guo, X.L, Shen, K, Lawrence, D.S, Almo, S.C, Zhang, Z.Y. Deposit date: 2003-07-04 Release date: 2003-08-12 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor. J.Biol.Chem., 278, 2003

携带强效选择性双齿抑制剂化合物2的蛋白酪氨酸磷酸酶1B（protein tyrosine phosphatase 1B）晶体结构描述组分：乙酸、镁离子、N-{1-[5-(1-氨基甲酰-2-巯基乙基氨基甲酰)戊基氨基甲酰]-2-[4-(二氟膦酰甲基)苯基]乙基}-3-{2-[4-(二氟膦酰甲基)苯基]乙酰氨基}琥珀酰胺酸，…… 作者：Sun J.P.、Fedorov A、Lee S.Y、Guo X.L、Shen K、Lawrence D.S、Almo S.C、Zhang Z.Y. 沉积日期：2003年7月4日发布日期：2003年8月12日最后修改日期：2023年8月16日实验方法：X射线衍射（分辨率2.15埃）引用文献：Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor. J. Biol. Chem., 278, 2003

创建时间：

2003-07-04