Preoperative primary tumor SUVmax on PET/CT correlates with Breslow thickness and is associated with survival in melanoma: A retrospective cohort study

Supplementary Table I. Demographics and tumor characteristics of 31 patients with residual primary melanoma tumors that underwent PET/CT.

Supplementary Figure 1.
Subgroup analysis according to melanoma stage. (a) Patients with early-stage melanoma (Stage I-II) show a moderately positive correlation between SUVmax and Breslow thickness (r=0.585). (b) Patients with advanced-stage melanoma (Stage III-IV) show a strong correlation between SUVmax and Breslow thickness (r=0.618).

Supplementary Figure 2.
(a) Receiver operating characteristic (ROC) curve analysis identifying an SUVmax cutoff of 4.945 for predicting overall survival in melanoma patients. (b) Kaplan-Meier survival analysis demonstrating significantly worse survival rates in patients with SUVmax ≥ 4.945 compared to those with SUVmax < 4.945 (p=0.04, by Generalized Wilcoxon method).

补充表I：31例接受PET/CT检查的原发性黑色素瘤残留病灶患者的人口学特征与肿瘤学特征。

补充图1：按黑色素瘤分期进行的亚组分析。（a）早期黑色素瘤（I-II期）患者的标准化摄取值最大值（SUVmax）与布雷斯洛厚度呈中度正相关（r=0.585）。（b）晚期黑色素瘤（III-IV期）患者的SUVmax与布雷斯洛厚度呈强相关（r=0.618）。

补充图2：（a）受试者工作特征（Receiver Operating Characteristic, ROC）曲线分析确定了用于预测黑色素瘤患者总生存期的SUVmax临界值4.945。（b）卡普兰-迈耶生存分析显示，SUVmax≥4.945的患者总生存期显著差于SUVmax<4.945的患者（p=0.04，采用广义威尔科克森法检验）。