Development of gene expression for an INH-responsive transcriptional regulator InbR. Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2

To further determine the gene expression profile of InbR, encoded by Rv0275c in Mycobacterium tuberculosis, whole genome microarray analysises were applied to inbR-overexpressing strain and wild type Mycobacterium bovis BCG. Comparison of the gene expression pattern of logarithmic growth phase wild-type M. bovis BCG and that of the inbR-overexpression strain revealed a total of 142 genes that were significantly up-regulated (2-fold to 187-fold, p 2.0 were selected for further analysis.