JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-styrylindolin-2-one

JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-styrylindolin-2-one Descriptor: (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime, Mitogen-activated protein kinase 10 Authors: Jacobs, M.D. Deposit date: 2009-02-13 Release date: 2009-04-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 19, 2009

与JNK3结合的(Z)-1-((6-氟-4H-苯并[d][1,3]二氧杂环己烯-8-基)甲基)-3-(羟基亚氨基)-4-苯乙烯基吲哚啉-2-酮。描述符：(3Z)-1-[(6-氟-4H-1,3-苯并二氧杂环己烯-8-基)甲基]-4-[(E)-2-苯基乙烯基]-1H-吲哚-2,3-二酮3-肟，丝裂原活化蛋白激酶10（Mitogen-activated protein kinase 10）。作者：Jacobs, M.D.。提交日期：2009-02-13。发布日期：2009-04-28。最后修改日期：2024-02-21。检测方法：X射线衍射（分辨率2.2埃）。引用文献：《基于结构的设计与N-苄基靛红肟类JNK3丝裂原活化蛋白激酶抑制剂的平行合成》，发表于Bioorg.Med.Chem.Lett.，第19卷，2009年。