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Supplemental Material: Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa

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NIAID Data Ecosystem2026-05-10 收录
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Supplemental Material for the manuscript titled "Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension", published in the Journal of the American Academy of Dermatology. Contents: Supplementary Methods 1. Prespecified safety topics of interest Supplementary Figure 1: BE HEARD I and II and BE HEARD Extension study design Supplementary Figure 2: Safety pooled data Supplementary Figure 3: Missing data handling Supplementary Figure 4: HiSCR50/75/90/100 over time in BKZ Total patients (mNRI [AE-LoE]) Supplementary Figure 5: Efficacy- and lesion-based outcomes over time in BKZ Total patients (MI [AE-LoE] and mNRI [AE-LoE]) Supplementary Table 1. HiSCR50/75/90/100 to Week 96 in patients receiving BKZ Q2W/Q4W/Q4W (OC)
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2025-11-11
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