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UPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs. Mus musculus

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NIAID Data Ecosystem2026-03-08 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA238821
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资源简介:
This report not only adds a novel mechanism to the current dogma on achieving global shortening of 3'UTRs, but also unveils a novel function of the NMD pathway in establishing tissue-specific transcriptome identity Overall design: We first generated prospermatogonia-specific Upf2 conditional knockout mice (Ddx4-Cre; Upf2 fl/Δ, hereafter called Ddx4-KO) by crossing Ddx4-Cre13 with Upf2 floxed.
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2014-02-19
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