Functional Microbial Responses to Alcohol Abstinence in Patients with Alcohol Use Disorder

Excessive alcohol consumption is associated with hepatic steatosis and dysregulation of the gut microbiota in patients with alcohol use disorder. However, how gut microbiota responds when patients stop drinking has not been well studied. In this study, we use shotgun metagenomic sequencing to elucidate the alterations in the functional capacity of gut microbiota in patients with alcohol use disorder when they stop drinking for two-weeks.